Infantile nephrotic syndrome.

[Congenital and infantile nephrotic syndrome].

Congenital nephrotic syndrome is present at birth or appears during the first three months of life and infantile nephrotic syndrome during the first year. Finnish type congenital nephrotic syndrome is an autosomal recessive disease. Nephrotic syndrome is present at birth, severe and does not respond to therapy. Infectious and nutritional complications are frequent. Renal function deteriorates n...

Cytomegalovirus infection can mimic genetic nephrotic syndrome: a case report

BACKGROUND Nephrotic syndrome is a relatively rare but serious condition in children. Infantile nephrotic syndrome often has a genetic origin; the treatment is then symptomatic, with a poor prognosis, and a rapid evolution to chronic kidney disease. However, non-genetic infantile nephrotic syndrome has been identified. Here we report for the first time in a child a nephrotic syndrome as the sol...

Nephrotic syndrome in childhood: genotype-phenotype association studies and screening for novel mutations

..............................................................................................................................xiv Introduction ............................................................................................................................1 What is Nephrotic Syndrome? .............................................................................................1 Patho...

Long-term azathioprine therapy in two children with steroid-dependent minimal-change nephrotic syndrome. H. Tanaka, N. Onodera and S. Waga Infantile pulmonary alveolar proteinosis with interstitial pneumonia: Bilateral simultaneous lung lavage utilizing extracorporeal membrane oxygenation and steroid therapy

Primary and secondary CoQ(10) deficiencies in humans.

CoQ(10) deficiencies are clinically and genetically heterogeneous. This syndrome has been associated with five major clinical phenotypes: (1) encephalomyopathy, (2) severe infantile multisystemic disease, (3) cerebellar ataxia, (4) isolated myopathy, and (5) nephrotic syndrome. In a few patients, pathogenic mutations have been identified in genes involved in the biosynthesis of CoQ(10) (prima...

Children with Steroid-resistant Nephrotic Syndrome: a Single-Center Study

Background and Aim: Steroid-resistant nephrotic syndrome (SRNS) accounts for 10%-20% of all cases of idiopathic nephrotic syndrome. These patients are at risk of developing end-stage renal disease. The aim of this study was to determine the demographic characteristics, renal biopsy findings, response to immunosuppressive treatment, and prognosis in pediatric patients with SRNS.Materials and Met...